Why msm with glucosamine chondroitin

Glucosamine and Joint Health Like chondroitin, glucosamine is produced naturally in your body and plays a role in joint health. It helps build and repair cartilage that connects the joints. Glucosamine possesses anti-inflammatory properties, and data suggests it may help relieve osteoarthritis pain, according to the American Academy of Orthopaedic Surgeons. Methylsulfonylmethane and Osteoarthritis MSM is a sulfur-containing compound that helps support tendons and muscles.

In the study, adults with mild-to-moderate knee osteoarthritis took MSM and glucosamine alone or in combination for 12 weeks. Conclusion: combination of glucosamine-chondroitinsulfate-methylsulfonylmethane showed clinical benefit for patients with knee OAK ellgren-Lawrence grade I-II compared with GC and placebo.

Keywords: Glucosamine; chondroitin sulfate; methylsufonylmethane; osteoarthritis. The information provided in this brochure does not replace the advice and guidance given by your doctor. If you have any questions about this supplement, please ask your physician. Glucosamine sulfate and chondroitin sulfate are naturally occurring substances found in the connective tissues of the body, including the cartilage that covers the ends of bones in the joints.

Glucosamine sulfate functions are the primary building block for proteoglycans, large molecules in cartilage that give it viscoelastic buffering properties. When taken orally, glucosamine sulfate is absorbed readily into the system and can be traced to cartilage as soon as four hours after consumption. Similar to non-steroidal anti-inflammatory drugs, glucosamine sulfate has been shown to have unique anti-inflammatory effects. Additionally, in some laboratory tests, the glucosamine supplement demonstrated a protective effect on the cartilage as well.

These studies suggest that glucosamine sulfate may inhibit the breakdown of cartilage associated with osteoarthritis and may have the potential to help build-up cartilage.

Glucosamine hydrochloride, another form of glucosamine, is available as a nutritional supplement and is considered to be as effective as the sulfate form although there are fewer completed studies to review. This hydrochloride form of glucosamine is more available for absorption into the body; therefore, a smaller dose delivers an equivalent amount in the system.

Chondroitin sulfate is a larger molecule also found in cartilage. Chondroitin sulfate has been studied much less extensively, but early results show that it also seems to work as an anti-inflammatory and reduces pain. MSM is a sulfur compound found in a wide variety of foods in your diet, such as fruit, vegetables, chocolate, tea, meat and seafood.

Because it may offer anti-inflammatory benefits, it's often found in joint supplements alongside glucosamine. Researchers examined the potential benefit of glucosamine alone and in combination with chondroitin on pain in knee osteoarthritis. Patients took 1, milligrams of glucosamine, 1, milligrams of chondroitin or both daily for 24 weeks.

The study concluded that the combination of glucosamine with chondroitin helps with moderate-to-severe knee pain, but is ineffective for mild pain.. A study published in June examined the efficacy of glucosamine alone and in combination with MSM on mild-to-moderate osteoarthritis.

Patients took milligrams of glucosamine, MSM or both three times daily for 12 weeks.